How did you first get involved as an advocate for those with scleroderma? He recently spoke with NIH MedlinePlus magazine about his advocacy and commitment to finding a cure for the disease. The 'Full House,' 'America's Funniest Home Videos,' and 'Fuller House' star has also won praise for his longtime advocacy on behalf of people battling scleroderma, a chronic autoimmune disease. Television actor and comedian Bob Saget has been making Americans laugh for decades.